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Neisseria meningitidis group C is an encapsulated bacterium that causes several diseases and is associated with high mortality rates, thereby constituting a serious public health problem. Thus, this study aimed to develop and validate a quality control method appropriate for the separation and quantification of free polysaccharide present in this conjugate N. CZE was used to remove unbound polysaccharide, and the electrophoretic conditions were varied to optimize resolution. We were able to develop and validate the proposed method, which was linear and showed a matrix effect. Repeatability and partial reproducibility of the method were also evaluated. The robustness results showed that control of temperature is required for reliable results. The validated method will be used to evaluate the conjugate batches submitted for Phase III clinical studies and for routine quality control of the conjugate vaccine.
I had to lobby and cry alot so I could bring my dog up, I am not sure how that will go because dogs have hair, need to go out, and the house might get messed up. If you are a Catholic girl dating a Mormon guy, then it may not be an issue with his parents. It also means that you have to give her something particular to do. It would put him in a position of feeling less and being looked down on.